Looks like their target is creatives to me. At least based on the video. But I'm itching to use one for both sketches and meeting notes.
With 10 bit colour support?
Do you mean 10 bits per channel? (i.e. 30-bit RGB.) The 10" retina iPads have routinely scored very well as 24-bit displays (not the best there are, but certainly they seem acceptable to a lot of professional photographers).
Apples move with the pencil is more targeted at businesses, hospitals and such. Win the users at home first, convert them easily at work later, at a higher price with a better margin.