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Re:A metabolic master switch underlying human obesity by jpollock on Monday August 24, 2015 @12:56PM (#10111223)
Myself, I've got a choice. Either I'm at a constant weight and I'm stupid due to low blood sugar, or I end up gaining weight. It's incredibly hard for me to find the right balance, I haven't managed it yet.
Re:A metabolic master switch underlying human obesity by ashark on Monday August 24, 2015 @01:27PM (#10111498)
My body's response to caloric restriction defies the math behind all the weight loss calculators I've seen. I don't even know how it's physically possible. Which sucks, because I find it fairly easy to limit my calorie intake, but have to eat at nearly concentration-camp levels to drop weight, which isn't fun.

However, my body responds very well to exercise, especially strength training. Less convenient (takes time, space, maybe some equipment) but, conversely, works way better for me than any tables/calculators I've seen say it should. You might try that, if you haven't.

Re:A metabolic master switch underlying human obesity by bosdev on Monday August 24, 2015 @12:58PM (#10111241)
Have you tried a ketogenic diet (low carb)?
Re:A metabolic master switch underlying human obesity by s3nnyy on Monday August 24, 2015 @01:23PM (#10111470)
What helped me was a a low-carb diet. After two weeks, cravings for sweets were gone and I felt great.