At work all our desktop software was ported to linux and it works fine. Linux web servers, of course, mostly. Well there are some non linux web applications and numerous embedded devices with web access.

All I run natively is MS office stuff, chrome/ff, and vpn/vnc/ssh remote access type stuff. I have a linux desktop box on my desk running all the remote stuff plus native emacs that I use for most real work, the little old MS box is just for opening Excel sheets and legacy Word docs occasionally.

Its been a long time since I've run a non-MS (and non-chrome non-FF) binary on a MS desktop at work. Many years at least. The future is the web not native apps. IT will no longer deploy native client apps as a policy, so its not like any are officially ever coming back.

Decades ago its amusing to recall how much work IT folks had to do to install dozens of 3rd party applications on desktops before we'd get to use them. We had multipage checkbox forms. Now its "office, FF and chrome" and some corporate secret sauce (corporate anti-virus whatever type stuff) and they're done. A more draconian employer would just install office and force minions to use MSIE. And google docs and competitors are taking over all non-corporate "productivity app" work. With web access and outlook web mail and free viewers, technically most worker drones don't need anything more than a MSIE bootloader, although its more humane to let people use FF / Chrome.

For most employees, if it boots and runs FF or chrome, that's all they use to earn their pay, so no difference if MS, linux, freebsd, or mac.