theddman

That's a great explanation! To add a cool point, the wobble position is frequently modified by highly specific enzymes to make it matter more. It's like some random protein mutated to do this modification and all of a sudden the organism got more RAM thus increasing it's fitness.

What do you mean synthesize? If you're starting from GHB, then you just titrate up with NaOH to ~neutral?

This article doesn't touch on how they also used mRNA coding for Cas9 instead of the protein itself.