sanjayjc
> One further patient, identified only as Drew, has been tumour-free for over four years after receiving immunotherapy.
The key part of the article, in my opinion, is this one (referring to the 13 year old):
> The scientific teams at Gustave Roussy cancer centre in France are now working intensively to understand what made his response possible. Their current hypothesis centres on what Dr Grill described as an extremely rare mutation in Lucas's tumour cells that made them unusually sensitive to everolimus by creating a dependency on the mTOR pathway. Researchers have begun creating tumour organoids, three-dimensional laboratory-grown models that mirror each patient's tumour's genetic characteristics, to test whether Lucas's specific cellular profile can be replicated.
What consolation is it for the subject to realize (via the blinking LED,) that their picture was taken; by then it could've been instantly shared? What recourse does Meta offer the victim after the fact?
A blinking LED light may thwart surreptitious recording but falls far short of real privacy.
[1] https://www.bloomberg.com/news/articles/2026-08-03/why-tungs...
I'd have thought the backup ELAC would've detected a divergence in its output relative to the primary's a lot sooner. And for something as critical as this, shouldn't there be 3 ELACs so majority voting could identify the anomalous one?
The word "halt" made it sound more permanent than this really is.
> While other magnet-free alternatives exist—such as centuries-old AC induction motors or switched reluctance motors—they are often heavy, inefficient workarounds. Similarly, ferrite magnets (like the ones announced by Ola Electric) come with performance tradeoffs.
Definitely sounds interesting but this line didn't make sense:
> Vimag’s roadmap includes designing its own Application-Specific Integrated Circuit (ASIC). This, too, like the motor would be virtual magnet based.
The author missed the main reason I favor working locally: privacy, not responsiveness.
We write prompts, launch agents and review what they produce.
What better tool to review that output than the one you know really well? For me and many others, that's Emacs and vi.
Secrets lying around everywhere
If secrets are moved from a local machine to the cloud, are they really secret any more?
Only 2?
I learned too late the lessons qwerpy expressed very well in https://news.ycombinator.com/item?id=48623191.
"how am I gonna teach all the good things"
I propose that you eschew the temptation to overwhelm the child with activities that you enjoy. A more subtle approach could work better: for instance, rather than insist on learning a specific music instrument in a rigid schedule, leave one within reach. Play it yourself and later (may be days later,) when the child picks it up, drop_the_phone and really, genuinely express your happiness and appreciation!
In general, let the child show you what intrigues them and then purchase whatever could help deepen their interest. However, now that you've made a purchase, don't go: "I bought this and now you've lost interest; such a waste of money." Their interests naturally bounce around and may come around again. See this not as a waste but an investment.
Anything (your time or your purchases,) that spurs them to discover their intrinsic motivation, is as an investment. Not all investments yield a positive ROI but given enough investments and enough time, your participation and your attention compounds!
I was with a young father this weekend, celebrating his son's 1st birthday. I'll leave you the advice I gave him and wish I had: time with your boy is not fungible. Given where you are in your career, you might feel extreme pressure to put off activities with your son. Don't! Rather than insist on doing something fun only when your calendar has a tiny opening, see every moment the child gives you his attention, as a tremendous gift. Don't waste it but (to the maximum extent possible,) drop whatever you're immersed in and fully give him your attention and time. Show him in that instant, how much he means to you. This too is an investment with a very long term ROI.
In due course, as a child grows up, the role their parents play in their mind-space, starts to shrink. Before then, there's a window in which a boy's hero is his father. Don't blow it by thinking you can ignore him then and make up later.
"how am I gonna teach all the good things"
Be open to your child teaching you many more good things too.
Finally, resist the temptation to show them a smartphone or screen, for as long you can [1]:
"These studies are more evidence that it’s a good idea to avoid lots of screen time in infancy (birth to 18 months). Infants just don’t have the cognitive skills to learn from screens at this age, and it gets in the way of activities that build brains, such as talking to infants, back-and-forth play, singing, or reading together. Research shows that products or programs claiming they are able to help babies learn language or regulate emotions are not telling the truth."
(father of two girls)
[1] https://www.aap.org/en/patient-care/media-and-children/cente...
[1] https://doublepulsar.com/fortibleed-75k-fortinet-firewalls-h...
Perhaps an e-ink display (either incorporated onto the device or affixed to the refrigerator) could display info that is likely to change very frequently. That's the only suggestion I can think to offer.
Best of luck on your venture!
"Millions of pounds have been saved by replacing a Palantir IT system which helps to find homes for Ukrainian refugees with one built by its own experts"
It is noteworthy that a government department decided it could meet its requirements without a 3rd party provider. Could be the start of a trend but a wholesale move away from PLTR this isn't.
"Statoliths are denser than a cell’s cytoplasm and can drift and sink through the cell, like a bit of sand in a jar of water. When a statolith finally settles to the bottom, its resting place on the cell’s membrane is a reflection of gravity’s direction and a signal for where a seed’s root or shoot should grow."
https://interestingengineering.com/innovation/scientists-ele...
With vi (after running "set -o vi"): <esc>kC
(k to move up back one position in history. C to "change" to the end of the line.)
This is equivalent to doing the following with "set -o emacs": <ctrl>pu
Regardless, use what you're comfortable with or can incrementally add to your muscle memory.
Is there a port to Apple silicon?
There's also "A Graduate Course in Applied Cryptography" [2]
Am I wrong that this is a double standard: being careful to protect oneself from a wayward agent with no regard for the real harm it could (and did) to another individual? And to casually dismiss this possibility with:
> At worst, maintainers can close the PR and block the account.
I question the entire premise of:
> Find bugs in science-related open source projects. Fix them. Open PRs.
Thinking of AI as "disembodied intelligence," one wonders how any agent can develop something we humans take for granted: reputation. And more than ever, reputation matters. How else can a maintainer know whether the agent that made a good fix is the same as the one proposing another? How can one be sure that all comments in a PR originated from the same agent?
> First, I’m a human typing this post. I’m not going to tell you who I am.
Why should anyone believe this? Nothing keeps an agent from writing this too.
> Secure (end-to-end encryption available)
It seems telegram bot conversations don't use the Secret Chat feature [1]. Even if they did, I'd be cautious [2].
[1] https://community.latenode.com/t/are-telegram-bot-conversati...
[2] https://blog.cryptographyengineering.com/2024/08/25/telegram...
> pointlessly going against expectations
If you're referring to the ribbon, I'm not sold on its superiority. The vast majority of other software still uses the familiar menu structure, which is what LO uses too.
Granted, well meaning educational programs expose students to MS Office and its paradigm, from an early age. For their sake, I eagerly await a coding assistant AI powerful enough to reskin LibreOffice to look just MS Office, ribbon and all.
[1] https://www.sliderulemuseum.com/REF/scales/MakeYourOwnSlideR...
[2] http://leewm.freeshell.org/origami/card-slide.pdf
[3] https://www.sliderulemuseum.com/SR_Scales.shtml#YingHum
[4] http://www.antiquark.com/sliderule/sim/virtual-slide-rule.ht...
This is what I was trying to get at in my other comment [1]!
My fascination stems from a belief: that slide rule usage helps users develop a certain intuition for numbers whereas the calculator doesn't. To illustrate, suppose someone tries to multiply 123 and 987 with a calculator but incorrectly punches in 123 and 187. My hypothesis is they'll look at the result but won't suspect any problem. The equivalent operation on a slide rule requires fewer physical actions and hence, is less error prone.
Do you think there's anything to this hypothesis?
"When a mold’s takeover of an artifact must be stopped, there’s gamma radiation—pelting it with electromagnetic energy from radioactive decay to kill fungi and spores. But this technique penetrates deeply and can extensively damage materials."