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medical_alt

That's interesting. Just take care with that. There's some epidemiological evidence that anticholenergics like clemastine may possibly contribute to dementia:

https://www.health.harvard.edu/blog/common-anticholinergic-d...

The data suggest correlation, not necessarily causation, but at the least I'd carefully investigate the risks before taking any anticholergic in such high doses. I do understand (with my own chronic health issues) that even with the risk of dementia later on, it may still be a possibility, depending on the severity of current symptoms.

I have chronic idiopathic axonal polyneuropathy (and several other chronic conditions) that have left me in near-constant pain (and at times with mobility issues, particularly the first year). It was initially thought to be possibly autoimmune in nature (I have two family members with 1 or more autoimmune diseases), but it was never confirmed.

I've been told that IvIG isn't even a good option for me, and in any case, I'm concerned about the at times severe side effects.

There are so many people around the world suffering from various forms of neuropathy, yet it seems to get relatively little attention. Some people are in wheelchairs, some in constant and severe pain, others lose control of their bladder or bowels, and some experience all of the above. Many millions of people worldwide. It seems like there would be a greater effort to come up with new therapeutics. At the very least, it's a huge market.