ktarnowski
When things go side-track (i.e. really bad) talk to his supervisor.
Do something light for a while. Spend more time with your family, close friends etc. Try something new and interesting. Then, after a time, ask yourself again what you really want to do and simply start over. By that time you should be level-headed and open-minded about your previous venture and use that experience to your advantage. Either bootstrap one of your ideas, join a start-up/company that you like or, well, do what you always wanted to do.
Naturally, take this advice, like any other, with a grain of salt. I'm not you; it's your life.
Flask, despite being a micro-framework, is extremely powerful. It's core is well-written and there's a lot of useful extensions out there (like Flask-WTF or Flask-Assets). Flask also works really well with Google App Engine (see example skeleton: https://github.com/kamalgill/flask-appengine-template; there's more on GitHub). With little effort you get WTForms and even Webassets support almost out of the box, in really elegant way.
Tornado will also do, since it's very similar to webapp and has very good templating system. However, since extensions ecosystem for Tornado is almost non-existent, one has to write more code to make up for it (e.g. integration with Webassets, management commands, OAuth support etc.).
There's also Tipfy, but I have absolutely no experience with it, so I can't vouch for it.