hfttrader
A second reason why they are compensated so highly is that they are working in a highly leveraged job where the labor cannot be easily be divided between multiple people. This is similar to how CEO's make a lot of money, because being a good CEO produces a lot of value for the company and the position cannot be split between multiple people. (I'm not trying to imply that traders produce as much value to society as CEO's do) Being a marginally better trader will make your firm millions more per year. Good hedge funds have 100-1000 million of assets under management per front-office employee. (For example, D.E. Shaw or Bridgewater Associates)
Transfers are slow because there is little need to transfer large amounts of money quickly, and slower transactions help address issues with fraud. If you are buying a car, or paying for a house there is little need for a fast transactions. So with BTC or USD, transferring large amounts of money will take days.
HFT definitely has high entry costs (10's of millions of dollars), and firms that aren't serious about HFT can't participate. Note that HFT only makes 2 billion a year, so they aren't actually missing out on that much. HFT just isn't a very big space, compared to long term investing, and doesn't represent very much movement of capital. (The wealthy don't really invest in HFT, since HFT firms generally don't accept outside capital, or need any substantial amount of capital to operate)
The main scenario where HFT firms increase volatility is when their algorithms break (either due to a programming error, or because they cease to accurately model the market due to a change in market conditions). In that case, the misfiring algorithm will increase the market volatility, and lose the HFT firm money.
You absolutely right that firms without co-located data centers are at a disadvantage. Thankfully, this only really matters if you are trying to compete with HFT firms. So it's not a big issue for people who trade on a longer time scales. The HFT firms do make some money off of these long term investors, and in exchange provide increased liquidity, decreased spreads, and decreased volatility. (if the HFT firms weren't offering the best prices for the stocks, then the long term investors wouldn't be buying from them)
HFT isn't based on market manipulation. Some HFT firms perform market manipulation, as do some non HFT firms, but this practice is illegal. (For example, newedge was recently fined for market manipulation)