bad_luck
Cars were invented for people with sufficient use of their limbs and eyesight. After their invention, the control systems were adapted for people who, for instance, can't use their legs. I don't know of any way they have been adapted for e.g. blind people. And yet, even though they are not accessible to a large fraction of disabled people, the world is better off with cars, designed for not-disabled people and then adapted as far as possible, than without cars.
That's all I'm getting at. Its too much of a constraint on invention, but likely to be adaptable later.
I agree that's important, but I don't think that a great OS should become just a good OS in pursuit of that goal. After the OS is made, it seems like there would absolutely be ways to make the system accessible as-needed.