Mieroels
Re:A Single Neuron May Cary Up to 1000 Genetic Mutations
on Monday October 05, 2015 @05:31AM (#10330698)
I think a lot of the mutations can be attributed to infidelities of single cell sequecing. The amplification of DNA that has to be done has a tendency to incorparate errors. If you start with a single copy of DNA then an copy error early in amplification will look like a mutation.
The neuron data is compared to non-single cell sequencing of heart cells.
Re:OpenSeadragon: A pure JavaScript high-resolution zoomable image viewer
on Wednesday September 16, 2015 @02:54PM (#10228887)
Openslide has a nice demo using OpenSeadragon. The histological slides can easily be > 100,000 pixels in width and height http://openslide.org/demo/