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CrispCas13

That's after DICER/Drosha processes the pre-miRNA/pri-miRNA transcripts. The pre-miRNA/pri-miRNAs transcripts can be a magnitude equal to or greater than 200 nts.
As added information: metformin, a common anti-diabetic drug, is a inhibitor of mTOR. It potential adverse effects are less severe than rapamycin but are still significant. Specifically, long term usage can cause renal damage. Its mechanism of action has yet to be fully elucidated.