Readability is in Safari, so many (many) millions of users. There are extensions for basically everything, bookmarklets for everything else, and many news-reading applications use the same scripts to render their 'text' views.

And popup / cookie blocking has been standard (not just common!) for a while, so I assume you didn't mean that.

I've been using Evernote Clearly for a while, which is easily the best extension for this in Chrome.

http://evernote.com/clearly/