Well, if you really want to use Lisp code and Python libraries, and are prepared to write a compiler, why not do the translation in the reverse direction? Write a compiler from Python to Lisp, and bring Python libraries to Lisp.

[edit: irrelevant stuff removed since parent was deleted]

It is definitely something to consider, and while I don't think translating Python to Common Lisp would be all that difficult, I do think that getting the C libraries that Python wraps working with CL might be a significant effort. A lot of the good libraries like csv, re, etc, are implemented in C if I remember correctly.